Specific genomic alterations and aggressive clinical features of sporadic thyroid carcinomas in children and adolescents: findings from an in-house cohort study

Specific genomic alterations and aggressive clinical features of sporadic thyroid carcinomas in children and adolescents: findings from an in-house cohort study

IntroductionPapillary thyroid carcinoma is the most common pathological subtype of thyroid cancer in both children/adolescents (TCCA) and adults (TCA). TCCA manifests more aggressive and invasive behaviors than TCA, which may be attributed to specific genomic alterations. MethodsTo better understand...

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Main Authors: Gongxun Tan, Yuguo Wang, Guoliang Zhang, Xian Wang, Yongzhen Ren, Qian Gu, Feiju Xu, Zhenwei Mao, Chunhe Shi, Hui Wang, Ting Wu, Xi Wei, Tengxu Zhang, Xiuying Li, Ying Xu, Shengsheng Ou, Xinping Wu, Gaolei Jia, Xiaoqin Qian
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Endocrinology
Subjects:
thyroid cancer
children and adolescents
adults
genomic alterations
clinical ultrasound manifestations
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1603571/full
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https://www.frontiersin.org/articles/10.3389/fendo.2025.1603571/full

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