Short- and long-term pathologic responses to quartz are induced by nearly free silanols formed during crystal fracturing

Short- and long-term pathologic responses to quartz are induced by nearly free silanols formed during crystal fracturing

Abstract Background Inhalation of respirable crystalline silica particles, including quartz, is associated with an increased risk of developing pathologies, including persistent lung inflammation, fibrosis, cancer, and systemic autoimmunity. We demonstrated that the nearly free silanols (NFS) genera...

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Main Authors: Cristina Pavan, Riccardo Leinardi, Anissa Benhida, Saloua Ibouraadaten, Yousof Yakoub, Sybille van den Brule, Dominique Lison, Francesco Turci, François Huaux
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Particle and Fibre Toxicology
Subjects:
Quartz
Silica
Respirable crystalline silica
Silanols
Inflammation
Fibrosis
Online Access:https://doi.org/10.1186/s12989-024-00611-8
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https://doi.org/10.1186/s12989-024-00611-8

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