Modeling TB-HIV Syndemic and Treatment
Tuberculosis (TB) and human immunodeficiency virus (HIV) can be considered a deadly human syndemic. In this paper, we formulate a model for TB and HIV transmission dynamics. The model considers both TB and acquired immune deficiency syndrome (AIDS) treatment for individuals with only one of the two...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2014-01-01
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| Series: | Journal of Applied Mathematics |
| Online Access: | http://dx.doi.org/10.1155/2014/248407 |
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| Summary: | Tuberculosis (TB) and human immunodeficiency virus (HIV) can be considered a deadly
human syndemic. In this paper, we formulate a model for TB and HIV transmission dynamics. The model considers both TB and acquired immune deficiency syndrome (AIDS)
treatment for individuals with only one of the two infectious diseases or both. The basic reproduction number and equilibrium points are determined and stability is analyzed. Through
simulations, we show that TB treatment for individuals with only TB infection reduces the
number of individuals that become coinfected with TB and HIV/AIDS and reduces the
diseases (TB and AIDS) induced deaths. Analogously, the treatment of individuals with
only AIDS also reduces the number of coinfected individuals. Further, TB treatment for
coinfected individuals in the active and latent stage of TB disease implies a decrease of the
number of individuals that passes from HIV-positive to AIDS. |
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| ISSN: | 1110-757X 1687-0042 |