Role of Radiotherapy in Modern Treatment of Hodgkin's Lymphoma

Hodgkin's Lymphoma was incurable until the advent of effective therapeutic radiation around the first half of the 20th century. As survival rates improved, the long-term toxicities from radiotherapy began to emerge. This together with the availability of effective chemotherapy has encouraged a...

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Main Authors: Kheng-Wei Yeoh, N. George Mikhaeel
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Advances in Hematology
Online Access:http://dx.doi.org/10.1155/2011/258797
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author Kheng-Wei Yeoh
N. George Mikhaeel
author_facet Kheng-Wei Yeoh
N. George Mikhaeel
author_sort Kheng-Wei Yeoh
collection DOAJ
description Hodgkin's Lymphoma was incurable until the advent of effective therapeutic radiation around the first half of the 20th century. As survival rates improved, the long-term toxicities from radiotherapy began to emerge. This together with the availability of effective chemotherapy has encouraged a combined modality approach for early-staged disease and the omission of radiotherapy in advanced-staged disease. The differing toxicities of radiotherapy and chemotherapy has promoted ongoing research to identify the utility of each of these modalities in the modern management of Hodgkin's Lymphoma. This article will provide a critical review of the developments and indications for modern radiotherapy, in context with advances in chemotherapy, for the treatment of Hodgkin's Lymphoma.
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institution Kabale University
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publishDate 2011-01-01
publisher Wiley
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spelling doaj-art-e6561cbf0e4e48fbb55aee8d51c3014a2025-02-03T06:06:38ZengWileyAdvances in Hematology1687-91041687-91122011-01-01201110.1155/2011/258797258797Role of Radiotherapy in Modern Treatment of Hodgkin's LymphomaKheng-Wei Yeoh0N. George Mikhaeel1Department of Clinical Oncology, Guy's and St. Thomas' Hospital, London, UKDepartment of Clinical Oncology, Guy's and St. Thomas' Hospital, London, UKHodgkin's Lymphoma was incurable until the advent of effective therapeutic radiation around the first half of the 20th century. As survival rates improved, the long-term toxicities from radiotherapy began to emerge. This together with the availability of effective chemotherapy has encouraged a combined modality approach for early-staged disease and the omission of radiotherapy in advanced-staged disease. The differing toxicities of radiotherapy and chemotherapy has promoted ongoing research to identify the utility of each of these modalities in the modern management of Hodgkin's Lymphoma. This article will provide a critical review of the developments and indications for modern radiotherapy, in context with advances in chemotherapy, for the treatment of Hodgkin's Lymphoma.http://dx.doi.org/10.1155/2011/258797
spellingShingle Kheng-Wei Yeoh
N. George Mikhaeel
Role of Radiotherapy in Modern Treatment of Hodgkin's Lymphoma
Advances in Hematology
title Role of Radiotherapy in Modern Treatment of Hodgkin's Lymphoma
title_full Role of Radiotherapy in Modern Treatment of Hodgkin's Lymphoma
title_fullStr Role of Radiotherapy in Modern Treatment of Hodgkin's Lymphoma
title_full_unstemmed Role of Radiotherapy in Modern Treatment of Hodgkin's Lymphoma
title_short Role of Radiotherapy in Modern Treatment of Hodgkin's Lymphoma
title_sort role of radiotherapy in modern treatment of hodgkin s lymphoma
url http://dx.doi.org/10.1155/2011/258797
work_keys_str_mv AT khengweiyeoh roleofradiotherapyinmoderntreatmentofhodgkinslymphoma
AT ngeorgemikhaeel roleofradiotherapyinmoderntreatmentofhodgkinslymphoma