Cyclooxygenase-2 Mediated Regulation of E-Cadherin Occurs in Conventional But Not Early-Onset Gastric Cancer Cell Lines
Background: COX-2 and E-cadherin, involved in invasion and metastasis, are molecules critical for gastric carcinogenesis. A relationship between them is documented in non-small cell lung and prostate cancer. We present novel evidence of a relationship between COX-2 and E-cadherin expression in gastr...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2009-01-01
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| Series: | Cellular Oncology |
| Online Access: | http://dx.doi.org/10.3233/CLO-2009-0496 |
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| _version_ | 1832567412358119424 |
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| author | R. Sitarz R. J. Leguit W. W. J. de Leng F. H. M. Morsink W. P. Polkowski R. Maciejewski G. J. A. Offerhaus A. N. Milne |
| author_facet | R. Sitarz R. J. Leguit W. W. J. de Leng F. H. M. Morsink W. P. Polkowski R. Maciejewski G. J. A. Offerhaus A. N. Milne |
| author_sort | R. Sitarz |
| collection | DOAJ |
| description | Background: COX-2 and E-cadherin, involved in invasion and metastasis, are molecules critical for gastric carcinogenesis. A relationship between them is documented in non-small cell lung and prostate cancer. We present novel evidence of a relationship between COX-2 and E-cadherin expression in gastric cancer. |
| format | Article |
| id | doaj-art-e63dbf24a9a049baa19cdf9376f7904f |
| institution | Kabale University |
| issn | 1570-5870 1875-8606 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cellular Oncology |
| spelling | doaj-art-e63dbf24a9a049baa19cdf9376f7904f2025-02-03T01:01:38ZengWileyCellular Oncology1570-58701875-86062009-01-0131647548510.3233/CLO-2009-0496Cyclooxygenase-2 Mediated Regulation of E-Cadherin Occurs in Conventional But Not Early-Onset Gastric Cancer Cell LinesR. Sitarz0R. J. Leguit1W. W. J. de Leng2F. H. M. Morsink3W. P. Polkowski4R. Maciejewski5G. J. A. Offerhaus6A. N. Milne7Department of Pathology, University Medical Centre, Utrecht, The NetherlandsDepartment of Pathology, University Medical Centre, Utrecht, The NetherlandsDepartment of Pathology, University Medical Centre, Utrecht, The NetherlandsDepartment of Pathology, University Medical Centre, Utrecht, The NetherlandsDepartment of Surgical Oncology, Medical University of Lublin, Lublin, PolandDepartment of Human Anatomy, Medical University of Lublin, Lublin, PolandDepartment of Pathology, University Medical Centre, Utrecht, The NetherlandsDepartment of Pathology, University Medical Centre, Utrecht, The NetherlandsBackground: COX-2 and E-cadherin, involved in invasion and metastasis, are molecules critical for gastric carcinogenesis. A relationship between them is documented in non-small cell lung and prostate cancer. We present novel evidence of a relationship between COX-2 and E-cadherin expression in gastric cancer.http://dx.doi.org/10.3233/CLO-2009-0496 |
| spellingShingle | R. Sitarz R. J. Leguit W. W. J. de Leng F. H. M. Morsink W. P. Polkowski R. Maciejewski G. J. A. Offerhaus A. N. Milne Cyclooxygenase-2 Mediated Regulation of E-Cadherin Occurs in Conventional But Not Early-Onset Gastric Cancer Cell Lines Cellular Oncology |
| title | Cyclooxygenase-2 Mediated Regulation of E-Cadherin Occurs in Conventional But Not Early-Onset Gastric Cancer Cell Lines |
| title_full | Cyclooxygenase-2 Mediated Regulation of E-Cadherin Occurs in Conventional But Not Early-Onset Gastric Cancer Cell Lines |
| title_fullStr | Cyclooxygenase-2 Mediated Regulation of E-Cadherin Occurs in Conventional But Not Early-Onset Gastric Cancer Cell Lines |
| title_full_unstemmed | Cyclooxygenase-2 Mediated Regulation of E-Cadherin Occurs in Conventional But Not Early-Onset Gastric Cancer Cell Lines |
| title_short | Cyclooxygenase-2 Mediated Regulation of E-Cadherin Occurs in Conventional But Not Early-Onset Gastric Cancer Cell Lines |
| title_sort | cyclooxygenase 2 mediated regulation of e cadherin occurs in conventional but not early onset gastric cancer cell lines |
| url | http://dx.doi.org/10.3233/CLO-2009-0496 |
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