Antisense Oligonucleotide-Capped Gold Nanoparticles as a Potential Strategy for Tackling Antimicrobial Resistance

Antisense Oligonucleotide-Capped Gold Nanoparticles as a Potential Strategy for Tackling Antimicrobial Resistance

Multidrug-resistant (MDR) bacterial pathogens pose a serious threat to global health, underscoring the urgent need for innovative therapeutic strategies. In this work, we designed and characterized thiol-modified antisense oligonucleotide-capped gold nanoparticles (ASO-AuNPs) to resensitize antibiot...

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Bibliographic Details
Main Authors: Cesar Rodolfo Garza-Cardenas, Angel Leon-Buitimea, A. A. Siller-Ceniceros, Jose Ruben Morones-Ramirez
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Microbiology Research
Subjects:
antisense oligonucleotide
gene silencing
gold nanoparticles
antimicrobial resistance
combination therapy
beta-lactam antibiotics
Online Access:https://www.mdpi.com/2036-7481/16/3/70
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