Comparison of associations suggests mainly distinct pools of genetic risk factors contribute to cisplatin-induced hearing loss and hearing difficulty in the general population

Cisplatin is an effective chemotherapeutic agent for treating many cancers. However, a major complication associated with cisplatin treatment is ototoxicity. Since the early 2000s, several genetic risk factors linked to cisplatin ototoxicity have been reported. However, the extent to which these gen...

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Bibliographic Details
Main Authors: Mohammad Shahbazi, Heather E. Wheeler, Xindi Zhang, Robert D. Frisina, Lois B. Travis, M. Eileen Dolan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Pharmacology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1577072/full
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