Nanodiamond-mediated delivery of microRNA-7 for the neuroprotection of dopaminergic neurons

Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the gradual loss of dopaminergic neurons in the substantia nigra and the accumulation of α-synuclein aggregates known as Lewy bodies. MicroRNA-7 (miR-7) targets the gene SNCA, which encodes α-synuclein, reducing its expression...

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Bibliographic Details
Main Authors: Yuping Han, Yue Yao, Xinyi Wen, Hao Wang, Shurong Li, Bingyin Su
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Bioengineering and Biotechnology
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Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2024.1480573/full
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