Changes in the Distribution of the α3 Na+/K+ ATPase Subunit in Heterozygous Lurcher Purkinje Cells as a Genetic Model of Chronic Depolarization during Development

A common assumption of excitotoxic mechanisms in the nervous system is that the ionic imbalance resulting from overstimulation of glutamate receptors and increased Na+ and Ca++ influx overwhelms cellular energy metabolic systems leading to cell death. The goal of this study was to examine how a chro...

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Bibliographic Details
Main Authors: Rebecca McFarland, Hadi S. Zanjani, Jean Mariani, Michael W. Vogel
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:International Journal of Cell Biology
Online Access:http://dx.doi.org/10.1155/2014/152645
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