Peripheral alveolar macrophages express more ACE2 immunoreactivity than in hilar area in human autopsied lung

Peripheral alveolar macrophages express more ACE2 immunoreactivity than in hilar area in human autopsied lung

Abstract Objective SARS-coronavirus 2 (SARS-CoV-2) is the cause of the coronavirus disease 19 (COVID-19). SARS-CoV-2 spike (S) glycoprotein binds to a cellular receptor angiotensin converting enzyme 2 (ACE2). COVID-19 pneumonia has a tendency to cause peripheral inflammation. To test the possibility...

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Bibliographic Details
Main Authors: Makoto Nogami, Hiromi Mutsuro-Aoki, Tomoaki Hoshi, Yoko Toukairin, Tomomi Arai, Tadashi Nishio
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Research Notes
Subjects:
SARS-CoV-2
COVID-19
ACE2
Immunohistochemistry
Type 2 alveolar epithelium
Alveolar macrophage
Online Access:https://doi.org/10.1186/s13104-025-07292-2
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https://doi.org/10.1186/s13104-025-07292-2

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