Maresin1 Alleviates Ischemia Reperfusion Injury After Lung Transplantation by Inhibiting Ferroptosis via the PKA-Hippo-YAP Signaling Pathway

Maresin1 Alleviates Ischemia Reperfusion Injury After Lung Transplantation by Inhibiting Ferroptosis via the PKA-Hippo-YAP Signaling Pathway

<b>Background</b>: Lung ischemia reperfusion injury (LIRI) is a severe complication after lung transplantation (LT). Ferroptosis contributes to the pathogenesis of LIRI. Maresin1 (MaR1) is an endogenous pro-resolving lipid mediator that exerts protective effects against multiorgan diseas...

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Bibliographic Details
Main Authors: Peng Deng, You Wu, Li Wan, Xiangfu Sun, Quanchao Sun
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Biomedicines
Subjects:
Maresin1
lung ischemia reperfusion injury
ferroptosis
signaling pathway
lung transplantation
Online Access:https://www.mdpi.com/2227-9059/13/7/1594
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