The Transcription Factor SOX18 Inhibitor Small Molecule 4 Is a Potential Treatment of Cancer‐Induced Lymphatic Metastasis and Lymphangiosarcoma

The Transcription Factor SOX18 Inhibitor Small Molecule 4 Is a Potential Treatment of Cancer‐Induced Lymphatic Metastasis and Lymphangiosarcoma

ABSTRACT Background Malignant tumors release growth factors, promoting lymphangiogenesis in primary tumors and draining sentinel lymph nodes, ultimately facilitating lymph node metastasis. As a malignant lymphatic tumor entity, lymphangiosarcomas are characterized by low survival rates and limited t...

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Bibliographic Details
Main Authors: Katja K. Koll, Martin M. Zimmermann, Patrick A. Will, Ulrich Kneser, Christoph Hirche
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Cancer Reports
Subjects:
cancer‐induced lymphatic metastasis
lymphangiosarcoma
lymphatic endothelial cells
MO‐LAS
Sm4
SOX18 inhibitor
Online Access:https://doi.org/10.1002/cnr2.70110
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https://doi.org/10.1002/cnr2.70110

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