Targeting Trefoil Factor Family 3 in Obstructive Airway Diseases: A Computational Approach to Novel Therapeutics

Background: Airway remodeling, a hallmark of chronic obstructive pulmonary disease (COPD) and mustard lung disease, is influenced by the Trefoil Factor 3 (TFF3). This study sought to pinpoint a compound with minimal toxicity that can effectively suppress TFF3 expression and activity.Methods: We empl...

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Bibliographic Details
Main Authors: Alireza Shahriary, Mohsen Sisakht, Masoud Arabfard, Esmaeil Behmard, Ali Najafi
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2025-03-01
Series:Iranian Journal of Medical Sciences
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Online Access:https://ijms.sums.ac.ir/article_50444_5ea4af1444f71536dca42520a297d76c.pdf
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