Paratesticular Serous Borderline Tumor in a Pediatric Patient
Tumors of the paratesticular region are generally tumors of slow growth, with little symptomatology and, in most cases, benign in nature; in this area, a borderline serous tumor may arise hypothetically from Müllerian metaplasia of the tunica vaginalis, which is histologically identical to its ovari...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020-01-01
|
| Series: | Case Reports in Pathology |
| Online Access: | http://dx.doi.org/10.1155/2020/8789143 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832567973201575936 |
|---|---|
| author | Itzel Araceli Ortiz Meza Marco Antonio Ponce Camacho Rodolfo Franco Márquez Mauricio Delgado Morquecho Raquel Garza Guajardo Oralia Barboza Quintana |
| author_facet | Itzel Araceli Ortiz Meza Marco Antonio Ponce Camacho Rodolfo Franco Márquez Mauricio Delgado Morquecho Raquel Garza Guajardo Oralia Barboza Quintana |
| author_sort | Itzel Araceli Ortiz Meza |
| collection | DOAJ |
| description | Tumors of the paratesticular region are generally tumors of slow growth, with little symptomatology and, in most cases, benign in nature; in this area, a borderline serous tumor may arise hypothetically from Müllerian metaplasia of the tunica vaginalis, which is histologically identical to its ovarian counterpart. We present a 10-year-old male, with right gynecomastia and ipsilateral hydrocele, showing an enlarged right testicle with a volume of 12 ml and a left testicle with a volume of 10 ml. A right orchiectomy was performed, which presented a poorly defined tan tumor of 1.8 cm that occupied the vaginal and epididymal tunica, and infiltrates the testicular parenchyma. Histological sections revealed a cystic neoplasm, with hierarchical papillary projections, covered by one or several epithelial columnar and hobnail cells with moderate atypia and scant mitosis. Immunohistochemical reactions were performed, resulting positive for PAX-8, epithelial membrane antigen, and CK7, confirming the diagnosis of borderline serous tumor. Since the first reported case in 1986, few have been reported, the majority of these in adults with only three cases in children. In the few cases reported, the prognosis is usually favorable after surgical resection, with disease-free follow-up for up to 18 years. |
| format | Article |
| id | doaj-art-e57dc38ba3e341f59546efdd95b4e7e1 |
| institution | Kabale University |
| issn | 2090-6781 2090-679X |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pathology |
| spelling | doaj-art-e57dc38ba3e341f59546efdd95b4e7e12025-02-03T01:00:11ZengWileyCase Reports in Pathology2090-67812090-679X2020-01-01202010.1155/2020/87891438789143Paratesticular Serous Borderline Tumor in a Pediatric PatientItzel Araceli Ortiz Meza0Marco Antonio Ponce Camacho1Rodolfo Franco Márquez2Mauricio Delgado Morquecho3Raquel Garza Guajardo4Oralia Barboza Quintana5Department of Pathological Anatomy and Cytopathology, Universidad Autonoma de Nuevo Leon, Hospital Universitario ‘Dr José Eleuterio González, Monterrey, Nuevo León 64460, MexicoDepartment of Pathological Anatomy and Cytopathology, Universidad Autonoma de Nuevo Leon, Hospital Universitario ‘Dr José Eleuterio González, Monterrey, Nuevo León 64460, MexicoDepartment of Pathological Anatomy and Cytopathology, Universidad Autonoma de Nuevo Leon, Hospital Universitario ‘Dr José Eleuterio González, Monterrey, Nuevo León 64460, MexicoDepartment of Pathological Anatomy and Cytopathology, Universidad Autonoma de Nuevo Leon, Hospital Universitario ‘Dr José Eleuterio González, Monterrey, Nuevo León 64460, MexicoDepartment of Pathological Anatomy and Cytopathology, Universidad Autonoma de Nuevo Leon, Hospital Universitario ‘Dr José Eleuterio González, Monterrey, Nuevo León 64460, MexicoDepartment of Pathological Anatomy and Cytopathology, Universidad Autonoma de Nuevo Leon, Hospital Universitario ‘Dr José Eleuterio González, Monterrey, Nuevo León 64460, MexicoTumors of the paratesticular region are generally tumors of slow growth, with little symptomatology and, in most cases, benign in nature; in this area, a borderline serous tumor may arise hypothetically from Müllerian metaplasia of the tunica vaginalis, which is histologically identical to its ovarian counterpart. We present a 10-year-old male, with right gynecomastia and ipsilateral hydrocele, showing an enlarged right testicle with a volume of 12 ml and a left testicle with a volume of 10 ml. A right orchiectomy was performed, which presented a poorly defined tan tumor of 1.8 cm that occupied the vaginal and epididymal tunica, and infiltrates the testicular parenchyma. Histological sections revealed a cystic neoplasm, with hierarchical papillary projections, covered by one or several epithelial columnar and hobnail cells with moderate atypia and scant mitosis. Immunohistochemical reactions were performed, resulting positive for PAX-8, epithelial membrane antigen, and CK7, confirming the diagnosis of borderline serous tumor. Since the first reported case in 1986, few have been reported, the majority of these in adults with only three cases in children. In the few cases reported, the prognosis is usually favorable after surgical resection, with disease-free follow-up for up to 18 years.http://dx.doi.org/10.1155/2020/8789143 |
| spellingShingle | Itzel Araceli Ortiz Meza Marco Antonio Ponce Camacho Rodolfo Franco Márquez Mauricio Delgado Morquecho Raquel Garza Guajardo Oralia Barboza Quintana Paratesticular Serous Borderline Tumor in a Pediatric Patient Case Reports in Pathology |
| title | Paratesticular Serous Borderline Tumor in a Pediatric Patient |
| title_full | Paratesticular Serous Borderline Tumor in a Pediatric Patient |
| title_fullStr | Paratesticular Serous Borderline Tumor in a Pediatric Patient |
| title_full_unstemmed | Paratesticular Serous Borderline Tumor in a Pediatric Patient |
| title_short | Paratesticular Serous Borderline Tumor in a Pediatric Patient |
| title_sort | paratesticular serous borderline tumor in a pediatric patient |
| url | http://dx.doi.org/10.1155/2020/8789143 |
| work_keys_str_mv | AT itzelaraceliortizmeza paratesticularserousborderlinetumorinapediatricpatient AT marcoantonioponcecamacho paratesticularserousborderlinetumorinapediatricpatient AT rodolfofrancomarquez paratesticularserousborderlinetumorinapediatricpatient AT mauriciodelgadomorquecho paratesticularserousborderlinetumorinapediatricpatient AT raquelgarzaguajardo paratesticularserousborderlinetumorinapediatricpatient AT oraliabarbozaquintana paratesticularserousborderlinetumorinapediatricpatient |