Regulation of proapoptotic mammalian ste20-like kinase MST2 by the IGF1-Akt pathway.
<h4>Background</h4>Hippo, a Drosophila serine/threonine kinase, promotes apoptosis and restricts cell growth and proliferation. Its mammalian homolog MST2 has been shown to play similar role and be regulated by Raf-1 via a kinase-independent mechanism and by RASSF family proteins through...
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| Main Authors: | Donghwa Kim, Shaokun Shu, Marc D Coppola, Satoshi Kaneko, Zeng-Qiang Yuan, Jin Q Cheng |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2010-03-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0009616&type=printable |
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