Regulation of proapoptotic mammalian ste20-like kinase MST2 by the IGF1-Akt pathway.

<h4>Background</h4>Hippo, a Drosophila serine/threonine kinase, promotes apoptosis and restricts cell growth and proliferation. Its mammalian homolog MST2 has been shown to play similar role and be regulated by Raf-1 via a kinase-independent mechanism and by RASSF family proteins through...

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Bibliographic Details
Main Authors: Donghwa Kim, Shaokun Shu, Marc D Coppola, Satoshi Kaneko, Zeng-Qiang Yuan, Jin Q Cheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0009616&type=printable
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