A noncarcinoma mouse cell line is nonsusceptible to Newcastle disease virus established by spontaneous immortalization

A noncarcinoma mouse cell line is nonsusceptible to Newcastle disease virus established by spontaneous immortalization

Abstract Newcastle disease virus (NDV), as an avian pathogen, can infect a broad spectrum of cell lines in vitro. However, noncarcinoma cell lines possessing nonsusceptibility to NDV are rare. Here, we isolated primary mouse embryonic fibroblasts (MEFs), which are nonsusceptible to NDV. MEF-derived...

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Main Authors: Hanlue Li, Zijie Zhou, Chuanyu Chang, Weiwei Shi, Yuzhen Li, Qiaolin Wei, Fanxing Meng, Jianxia Tian, Qiqi Hao, Jinming Liu, Haijin Liu, Zengqi Yang, Sa Xiao
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
NDV
Nonsusceptibility
SLM-21
Spontaneous immortalization
MEF
Online Access:https://doi.org/10.1038/s41598-025-14404-2
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https://doi.org/10.1038/s41598-025-14404-2

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