Insightful chemistry of molecular docking studies and ADMET profiling of 4-amino-1,2,4-triazole scaffolds as potential inhibitor of DprE1 enzymes as antitubercular agents

Insightful chemistry of molecular docking studies and ADMET profiling of 4-amino-1,2,4-triazole scaffolds as potential inhibitor of DprE1 enzymes as antitubercular agents

Abstract Background Airborne transmission of the bacterial illness tuberculosis (TB) is attributed to Mycobacterium tuberculosis (Mtb). Mycobacterium tuberculosis, a multidrug-resistant strain, spreads quickly and is the cause of multidrug-resistant tuberculosis (MDRTB). A study was conducted to inv...

Full description

Saved in:
Bibliographic Details
Main Authors: Santosh Prasad Chaudhary Kurmi, Dipanjan Karati
Format: Article
Language:English
Published: Springer 2025-06-01
Series:Discover Chemistry
Subjects:
DprE1 enzyme
Tuberculosis
Toxicity prediction
Retrobiocat route
Bioactivity radar analysis
Online Access:https://doi.org/10.1007/s44371-025-00208-w
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1007/s44371-025-00208-w

Similar Items