Cold atmospheric plasma effectively kills chordoma cells through induction of intracellular reactive oxygen species

Abstract Chordomas remain one of the most difficult-to-treat of skull base tumors. The best chance of survival and cure to date is with en bloc radical surgical resection, followed by adjuvant radiotherapy. Oftentimes, tumor infiltration into functionally critical, or difficult-to-access areas, prec...

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Main Authors: Sophie Peeters, Peter B. Wu, Blake Haist, Amber Armellini, Wi Jin Kim, Zhitong Chen, Richard Obenchain, George Ayad, Weihong Ge, Aparna Bhaduri, Graeme Sabiston, Robert M. Prins, Richard Wirz, Anthony C. Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-05916-y
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