Body Mass Index Trajectories during 6–18 Years Old and the Risk of Hypertension in Young Adult: A Longitudinal Study in Chinese Population
Background. Overweight/obesity in childhood is suggested to increase the risk of hypertension later in life. We aimed to assess whether and how body mass index (BMI) trajectories during 6–18 years of age are associated with hypertension in young adulthood (18–37 years) in the Chinese population. Met...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | International Journal of Hypertension |
| Online Access: | http://dx.doi.org/10.1155/2021/6646868 |
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| author | Haoyue Teng Jia Hu Wenxin Ge Qiling Dai Ji Liu Chengqi Xiao Jieyun Yin Xiaoyan Zhu |
| author_facet | Haoyue Teng Jia Hu Wenxin Ge Qiling Dai Ji Liu Chengqi Xiao Jieyun Yin Xiaoyan Zhu |
| author_sort | Haoyue Teng |
| collection | DOAJ |
| description | Background. Overweight/obesity in childhood is suggested to increase the risk of hypertension later in life. We aimed to assess whether and how body mass index (BMI) trajectories during 6–18 years of age are associated with hypertension in young adulthood (18–37 years) in the Chinese population. Methods. Based on the China Health and Nutrition Survey (CHNS), a total of 1,872 participants who received ≥2 measurements of BMI during 6–18 years and had assessment of blood pressure (BP) in young adulthood were included. BMI trajectories were explored using latent class growth mixture models, and associations between identified trajectories with hypertension in young adulthood were examined by logistic regression analyses. Results. Five heterogeneous BMI trajectories were identified: the low slow-increasing (20.03%), low moderate-increasing (56.14%), low rapid-increasing (17.04%), moderate-increasing (3.63%), and elevated-decreasing (3.15%) groups. Compared with the low slow-increasing group, another three increasing groups had gradually elevated risk of hypertension, yielding maximally adjusted odds ratio (95% confidence interval) (OR (95% CI)) of 2.48 (1.39–4.42), 3.24 (1.66–6.31), and 3.28 (1.19–9.08), respectively, whereas the elevated-decreasing group reversed overweight/obesity to normal weight in childhood, rendering its association with hypertension as not statistically significant (OR (95% CI) = 2.74 (0.98–7.65)). Conclusion. Our study indicates that there are varied BMI trajectories from childhood to adulthood and that an elevated BMI trajectory during childhood is related with an increased risk of hypertension in young adulthood. In contrast, weight loss of children with high initial BMI may mitigate or reverse the risk. Our findings emphasize the importance of BMI continuous monitoring during early life. |
| format | Article |
| id | doaj-art-e4b342eb71ee45c9b00c17619a0eefff |
| institution | Kabale University |
| issn | 2090-0384 2090-0392 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Hypertension |
| spelling | doaj-art-e4b342eb71ee45c9b00c17619a0eefff2025-02-03T07:24:04ZengWileyInternational Journal of Hypertension2090-03842090-03922021-01-01202110.1155/2021/66468686646868Body Mass Index Trajectories during 6–18 Years Old and the Risk of Hypertension in Young Adult: A Longitudinal Study in Chinese PopulationHaoyue Teng0Jia Hu1Wenxin Ge2Qiling Dai3Ji Liu4Chengqi Xiao5Jieyun Yin6Xiaoyan Zhu7Department of Epidemiology and Health Statistics, Medical College of Soochow University, Suzhou, ChinaSuzhou Center for Disease Prevention and Control, Suzhou, Jiangsu 215004, ChinaDepartment of Epidemiology and Health Statistics, Medical College of Soochow University, Suzhou, ChinaDepartment of Epidemiology and Health Statistics, Medical College of Soochow University, Suzhou, ChinaDepartment of Epidemiology and Health Statistics, Medical College of Soochow University, Suzhou, ChinaDepartment of Epidemiology and Health Statistics, Medical College of Soochow University, Suzhou, ChinaDepartment of Epidemiology and Health Statistics, Medical College of Soochow University, Suzhou, ChinaSuzhou Center for Disease Prevention and Control, Suzhou, Jiangsu 215004, ChinaBackground. Overweight/obesity in childhood is suggested to increase the risk of hypertension later in life. We aimed to assess whether and how body mass index (BMI) trajectories during 6–18 years of age are associated with hypertension in young adulthood (18–37 years) in the Chinese population. Methods. Based on the China Health and Nutrition Survey (CHNS), a total of 1,872 participants who received ≥2 measurements of BMI during 6–18 years and had assessment of blood pressure (BP) in young adulthood were included. BMI trajectories were explored using latent class growth mixture models, and associations between identified trajectories with hypertension in young adulthood were examined by logistic regression analyses. Results. Five heterogeneous BMI trajectories were identified: the low slow-increasing (20.03%), low moderate-increasing (56.14%), low rapid-increasing (17.04%), moderate-increasing (3.63%), and elevated-decreasing (3.15%) groups. Compared with the low slow-increasing group, another three increasing groups had gradually elevated risk of hypertension, yielding maximally adjusted odds ratio (95% confidence interval) (OR (95% CI)) of 2.48 (1.39–4.42), 3.24 (1.66–6.31), and 3.28 (1.19–9.08), respectively, whereas the elevated-decreasing group reversed overweight/obesity to normal weight in childhood, rendering its association with hypertension as not statistically significant (OR (95% CI) = 2.74 (0.98–7.65)). Conclusion. Our study indicates that there are varied BMI trajectories from childhood to adulthood and that an elevated BMI trajectory during childhood is related with an increased risk of hypertension in young adulthood. In contrast, weight loss of children with high initial BMI may mitigate or reverse the risk. Our findings emphasize the importance of BMI continuous monitoring during early life.http://dx.doi.org/10.1155/2021/6646868 |
| spellingShingle | Haoyue Teng Jia Hu Wenxin Ge Qiling Dai Ji Liu Chengqi Xiao Jieyun Yin Xiaoyan Zhu Body Mass Index Trajectories during 6–18 Years Old and the Risk of Hypertension in Young Adult: A Longitudinal Study in Chinese Population International Journal of Hypertension |
| title | Body Mass Index Trajectories during 6–18 Years Old and the Risk of Hypertension in Young Adult: A Longitudinal Study in Chinese Population |
| title_full | Body Mass Index Trajectories during 6–18 Years Old and the Risk of Hypertension in Young Adult: A Longitudinal Study in Chinese Population |
| title_fullStr | Body Mass Index Trajectories during 6–18 Years Old and the Risk of Hypertension in Young Adult: A Longitudinal Study in Chinese Population |
| title_full_unstemmed | Body Mass Index Trajectories during 6–18 Years Old and the Risk of Hypertension in Young Adult: A Longitudinal Study in Chinese Population |
| title_short | Body Mass Index Trajectories during 6–18 Years Old and the Risk of Hypertension in Young Adult: A Longitudinal Study in Chinese Population |
| title_sort | body mass index trajectories during 6 18 years old and the risk of hypertension in young adult a longitudinal study in chinese population |
| url | http://dx.doi.org/10.1155/2021/6646868 |
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