Designing a Sulfur Vacancy Redox Disruptor for Photothermoelectric and Cascade-Catalytic-Driven Cuproptosis–Ferroptosis–Apoptosis Therapy

Designing a Sulfur Vacancy Redox Disruptor for Photothermoelectric and Cascade-Catalytic-Driven Cuproptosis–Ferroptosis–Apoptosis Therapy

Highlights The glycometabolism and enzyme activity of Cu2MnS3-x-PEG/glucose oxidase (MCPG) achieve a cascade catalytic reaction, continuously replenishing the deficient H2O2 and O2 and inducing adequate reactive oxygen species supply. Density functional theory calculations indicate that Mn doping fa...

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Main Authors: Mengshu Xu, Jingwei Liu, Lili Feng, Jiahe Hu, Wei Guo, Huiming Lin, Bin Liu, Yanlin Zhu, Shuyao Li, Elyor Berdimurodov, Avez Sharipov, Piaoping Yang
Format: Article
Language:English
Published: SpringerOpen 2025-07-01
Series:Nano-Micro Letters
Subjects:
Cuproptosis
Enzyme catalysis
Immunology
Photothermoelectric catalysis
Vacancy defects
Online Access:https://doi.org/10.1007/s40820-025-01828-8
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https://doi.org/10.1007/s40820-025-01828-8

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