Cardiac muscle organization revealed in 3-D by imaging whole-mount mouse hearts using two-photon fluorescence and confocal microscopy

The ability to image the entire adult mouse heart at high resolution in 3-D would provide enormous advantages in the study of heart disease. However, a technique for imaging nuclear/cellular detail as well as the overall structure of the entire heart in 3-D with minimal effort is lacking. To solve t...

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Bibliographic Details
Main Authors: Mayandi Sivaguru, Glenn Fried, Barghav S. Sivaguru, Vignesh A. Sivaguru, Xiaochen Lu, Kyung Hwa Choi, M Taher A Saif, Brian Lin, Sakthivel Sadayappan
Format: Article
Language:English
Published: Taylor & Francis Group 2015-11-01
Series:BioTechniques
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Online Access:https://www.future-science.com/doi/10.2144/000114356
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