Functional T cell response to COVID-19 vaccination with or without natural infection with SARS-CoV-2 in adults and children

Functional T cell response to COVID-19 vaccination with or without natural infection with SARS-CoV-2 in adults and children

Abstract Severe COVID-19 is rare in children suggesting differences in immune response between children and adults. Limited information is available on how cellular immunity is modulated by COVID-19 vaccination and prior infection, and whether it is differentially modulated in children compared to a...

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Main Authors: Evana Akhtar, Rakib Ullah Kuddusi, Md. Tanvir Talukder, Md. Jakarea, Md. Ahsanul Haq, Md. Shamim Hossain, Maya Vandenent, Mohammad Zahirul Islam, Rashid U. Zaman, Abdur Razzaque, Protim Sarker, Rubhana Raqib
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Cytotoxic T lymphocyte
Perforin
Granzyme B
IFN-γ
Cellular immunity
Online Access:https://doi.org/10.1038/s41598-025-95870-6
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https://doi.org/10.1038/s41598-025-95870-6

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