Coke zero for the zero: A randomized controlled trial examining coke zero consumption on night call inpatient course and mortality

Background Coca-Cola and Cola-Cola Zero Sugar are commonly consumed beverages by healthcare professionals. Medical superstitions abound about whether Cola-Cola Zero sugar consumption affects night call outcomes. Objectives The current study aimed to determine whether Coca-Cola Zero Sugar, compared t...

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Main Authors: Yu Heng Kwan, Haoming Tang, Lihua Qi, Angela Frances Hui Wen Yap, Linxuan Yan, Yi Xin Li, Andrea Zhe Ern Lee, Antoinette Shui Wen Fong, Yarn Kit Chan, Feng Yi Low, Charmaine Wai Yan Sum, Benjamin Jun Jie Seng, Sungwon Yoon, Truls Østbye, Sheryl Shien Wen Gan, Haur Yueh Lee, Warren Fong
Format: Article
Language:English
Published: SAGE Publishing 2025-01-01
Series:Proceedings of Singapore Healthcare
Online Access:https://doi.org/10.1177/20101058251318113
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author Yu Heng Kwan
Haoming Tang
Lihua Qi
Angela Frances Hui Wen Yap
Linxuan Yan
Yi Xin Li
Andrea Zhe Ern Lee
Antoinette Shui Wen Fong
Yarn Kit Chan
Feng Yi Low
Charmaine Wai Yan Sum
Benjamin Jun Jie Seng
Sungwon Yoon
Truls Østbye
Sheryl Shien Wen Gan
Haur Yueh Lee
Warren Fong
author_facet Yu Heng Kwan
Haoming Tang
Lihua Qi
Angela Frances Hui Wen Yap
Linxuan Yan
Yi Xin Li
Andrea Zhe Ern Lee
Antoinette Shui Wen Fong
Yarn Kit Chan
Feng Yi Low
Charmaine Wai Yan Sum
Benjamin Jun Jie Seng
Sungwon Yoon
Truls Østbye
Sheryl Shien Wen Gan
Haur Yueh Lee
Warren Fong
author_sort Yu Heng Kwan
collection DOAJ
description Background Coca-Cola and Cola-Cola Zero Sugar are commonly consumed beverages by healthcare professionals. Medical superstitions abound about whether Cola-Cola Zero sugar consumption affects night call outcomes. Objectives The current study aimed to determine whether Coca-Cola Zero Sugar, compared to regular Coca-Cola, is associated with any differences in inpatient admissions and mortality of patients on night calls. Methods A double-blinded randomized controlled trial was conducted in the Division of Medicine, Singapore General Hospital, Singapore involving junior doctors from January 2024 to February 2024.The primary outcome was the number of ward admissions under the night call doctor’s care. Secondary outcomes involved the number of inpatient deaths, high-dependency or intensive care admissions, the number of hours slept by the doctor, the number of steps walked by the doctor, and the level of sleepiness of the doctor on call. Results 203 participants consented and were randomized (44.9%). The data of 198 participants were included for analysis (97.5%). No significant differences were detected in the number of ward admissions between the Coca-Cola Zero Sugar group and the regular Coca-Cola group. For secondary outcomes, a significant difference was present between the two groups in the Karolinska Sleepiness Scale score ( p -value = .0413). Other secondary outcomes did not demonstrate significant differences between the two groups. Conclusions No convincing evidence was present to support the consumption of Coca-Cola Zero Sugar versus the regular Coca-Cola had significant differences in the number of inpatient admissions and mortality in night call duties.
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spelling doaj-art-e3de78bbce5a45e3a2f6aeecff2e9f052025-01-30T06:03:20ZengSAGE PublishingProceedings of Singapore Healthcare2059-23292025-01-013410.1177/20101058251318113Coke zero for the zero: A randomized controlled trial examining coke zero consumption on night call inpatient course and mortalityYu Heng KwanHaoming TangLihua QiAngela Frances Hui Wen YapLinxuan YanYi Xin LiAndrea Zhe Ern LeeAntoinette Shui Wen FongYarn Kit ChanFeng Yi LowCharmaine Wai Yan SumBenjamin Jun Jie SengSungwon YoonTruls ØstbyeSheryl Shien Wen GanHaur Yueh LeeWarren FongBackground Coca-Cola and Cola-Cola Zero Sugar are commonly consumed beverages by healthcare professionals. Medical superstitions abound about whether Cola-Cola Zero sugar consumption affects night call outcomes. Objectives The current study aimed to determine whether Coca-Cola Zero Sugar, compared to regular Coca-Cola, is associated with any differences in inpatient admissions and mortality of patients on night calls. Methods A double-blinded randomized controlled trial was conducted in the Division of Medicine, Singapore General Hospital, Singapore involving junior doctors from January 2024 to February 2024.The primary outcome was the number of ward admissions under the night call doctor’s care. Secondary outcomes involved the number of inpatient deaths, high-dependency or intensive care admissions, the number of hours slept by the doctor, the number of steps walked by the doctor, and the level of sleepiness of the doctor on call. Results 203 participants consented and were randomized (44.9%). The data of 198 participants were included for analysis (97.5%). No significant differences were detected in the number of ward admissions between the Coca-Cola Zero Sugar group and the regular Coca-Cola group. For secondary outcomes, a significant difference was present between the two groups in the Karolinska Sleepiness Scale score ( p -value = .0413). Other secondary outcomes did not demonstrate significant differences between the two groups. Conclusions No convincing evidence was present to support the consumption of Coca-Cola Zero Sugar versus the regular Coca-Cola had significant differences in the number of inpatient admissions and mortality in night call duties.https://doi.org/10.1177/20101058251318113
spellingShingle Yu Heng Kwan
Haoming Tang
Lihua Qi
Angela Frances Hui Wen Yap
Linxuan Yan
Yi Xin Li
Andrea Zhe Ern Lee
Antoinette Shui Wen Fong
Yarn Kit Chan
Feng Yi Low
Charmaine Wai Yan Sum
Benjamin Jun Jie Seng
Sungwon Yoon
Truls Østbye
Sheryl Shien Wen Gan
Haur Yueh Lee
Warren Fong
Coke zero for the zero: A randomized controlled trial examining coke zero consumption on night call inpatient course and mortality
Proceedings of Singapore Healthcare
title Coke zero for the zero: A randomized controlled trial examining coke zero consumption on night call inpatient course and mortality
title_full Coke zero for the zero: A randomized controlled trial examining coke zero consumption on night call inpatient course and mortality
title_fullStr Coke zero for the zero: A randomized controlled trial examining coke zero consumption on night call inpatient course and mortality
title_full_unstemmed Coke zero for the zero: A randomized controlled trial examining coke zero consumption on night call inpatient course and mortality
title_short Coke zero for the zero: A randomized controlled trial examining coke zero consumption on night call inpatient course and mortality
title_sort coke zero for the zero a randomized controlled trial examining coke zero consumption on night call inpatient course and mortality
url https://doi.org/10.1177/20101058251318113
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