METTL3-mediated m6A modification of circSTAT6 modulates miR-188-3p/Beclin1 axis to promote osteogenic differentiation of mesenchymal stem cells

Abstract Background The role of N6-methyladenosine (m6A)-modified circRNAs in disease progression is of great significance. However, the specific impact of m6A modification of circSTAT6 on osteoporosis (OP) is still uncertain. Methods The qRT-PCR was employed to assess the levels of METTL3, circSTAT...

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Bibliographic Details
Main Authors: Yue Luo, Yubo Shi, Yanqing Wu, Hui Cao
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-025-05720-4
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