SOSTDC1 downregulation in CD4+ T cells confers protection against obesity-induced insulin resistance

SOSTDC1 downregulation in CD4+ T cells confers protection against obesity-induced insulin resistance

Summary: Adipose-resident T cells play a crucial role in the development of obesity-induced insulin resistance. However, the specific mechanisms, particularly those involving non-immune cytokines, remain unclear. Here, we report significantly elevated levels of sclerostin domain-containing protein 1...

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Bibliographic Details
Main Authors: Dehai Li, Jing Zhu, Mingyue Zhang, Qiping Shi, Rong Guo, Daming Zhang, Pei Zheng, Hua Zhang, Guangqiang Li, Jie Wu, Guodong Sun, Qiong Wen, Jingyi Tan, Zonghua Liu, Xindong Liu, Hengwen Yang, Hongyun Lu, Guangchao Cao, Zhinan Yin, Qian Wang
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Cell Reports
Subjects:
CP: Immunology
CP: Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725002670
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