The Impact of <i>Lactobacillus reuteri</i> on Oral and Systemic Health: A Comprehensive Review of Recent Research
Oral diseases, particularly dental caries and periodontal disease, pose significant global health challenges. The imbalance of the oral microbiota plays a key role in the occurrence of these diseases, prompting researchers to seek new strategies to restore oral ecological balance. <i>Lactobaci...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-12-01
|
| Series: | Microorganisms |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-2607/13/1/45 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832587958240149504 |
|---|---|
| author | Zihui Liu Qing Cao Wenqing Wang Bowen Wang Yilun Yang Cory J. Xian Tiejun Li Yuankun Zhai |
| author_facet | Zihui Liu Qing Cao Wenqing Wang Bowen Wang Yilun Yang Cory J. Xian Tiejun Li Yuankun Zhai |
| author_sort | Zihui Liu |
| collection | DOAJ |
| description | Oral diseases, particularly dental caries and periodontal disease, pose significant global health challenges. The imbalance of the oral microbiota plays a key role in the occurrence of these diseases, prompting researchers to seek new strategies to restore oral ecological balance. <i>Lactobacillus reuteri</i> is a Gram-positive rod-shaped bacterium that exists in various body parts of humans, including the gastrointestinal tract, urinary tract, skin, and so on. This species has a potentially positive impact on oral health and plays an important role in maintaining systemic health. Recent studies have explored the application of <i>Lactobacillus reuteri</i> in the prevention and treatment of oral diseases, and its impact on systemic health has also been preliminarily revealed. The current review summarizes the role of <i>Lactobacillus reuteri</i> in oral health and systemic health and outlines its potential applications in the future. <i>Lactobacillus reuteri</i> has shown promising prospects in treating non-communicable biofilm-dependent oral diseases, but its mechanism of action and efficacy still need further research. In addition, <i>Lactobacillus reuteri</i> has also displayed some potential benefits in promoting overall health. Future research should focus on revealing the specific pathways of action of <i>Lactobacillus reuteri</i>, screening for the most beneficial strains, determining the most effective drug delivery strategies, developing oral and systemic health products based on <i>Lactobacillus reuteri</i>, and ensuring their safety in clinical applications. |
| format | Article |
| id | doaj-art-e34f675b3fed4a9eb99b865061bf55b5 |
| institution | Kabale University |
| issn | 2076-2607 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj-art-e34f675b3fed4a9eb99b865061bf55b52025-01-24T13:42:25ZengMDPI AGMicroorganisms2076-26072024-12-011314510.3390/microorganisms13010045The Impact of <i>Lactobacillus reuteri</i> on Oral and Systemic Health: A Comprehensive Review of Recent ResearchZihui Liu0Qing Cao1Wenqing Wang2Bowen Wang3Yilun Yang4Cory J. Xian5Tiejun Li6Yuankun Zhai7School of Stomatology, Henan University, Kaifeng 475004, ChinaSchool of Stomatology, Henan University, Kaifeng 475004, ChinaSchool of Stomatology, Henan University, Kaifeng 475004, ChinaSchool of Stomatology, Henan University, Kaifeng 475004, ChinaSchool of Stomatology, Henan University, Kaifeng 475004, ChinaUniSA Clinical and Health Sciences, University of South Australia, Adelaide, SA 5001, AustraliaSchool of Stomatology, Henan University, Kaifeng 475004, ChinaSchool of Stomatology, Henan University, Kaifeng 475004, ChinaOral diseases, particularly dental caries and periodontal disease, pose significant global health challenges. The imbalance of the oral microbiota plays a key role in the occurrence of these diseases, prompting researchers to seek new strategies to restore oral ecological balance. <i>Lactobacillus reuteri</i> is a Gram-positive rod-shaped bacterium that exists in various body parts of humans, including the gastrointestinal tract, urinary tract, skin, and so on. This species has a potentially positive impact on oral health and plays an important role in maintaining systemic health. Recent studies have explored the application of <i>Lactobacillus reuteri</i> in the prevention and treatment of oral diseases, and its impact on systemic health has also been preliminarily revealed. The current review summarizes the role of <i>Lactobacillus reuteri</i> in oral health and systemic health and outlines its potential applications in the future. <i>Lactobacillus reuteri</i> has shown promising prospects in treating non-communicable biofilm-dependent oral diseases, but its mechanism of action and efficacy still need further research. In addition, <i>Lactobacillus reuteri</i> has also displayed some potential benefits in promoting overall health. Future research should focus on revealing the specific pathways of action of <i>Lactobacillus reuteri</i>, screening for the most beneficial strains, determining the most effective drug delivery strategies, developing oral and systemic health products based on <i>Lactobacillus reuteri</i>, and ensuring their safety in clinical applications.https://www.mdpi.com/2076-2607/13/1/45<i>Lactobacillus reuteri</i>microbiomeperiodontal diseasesoral mucosal diseasesdental cariesgastrointestinal diseases |
| spellingShingle | Zihui Liu Qing Cao Wenqing Wang Bowen Wang Yilun Yang Cory J. Xian Tiejun Li Yuankun Zhai The Impact of <i>Lactobacillus reuteri</i> on Oral and Systemic Health: A Comprehensive Review of Recent Research Microorganisms <i>Lactobacillus reuteri</i> microbiome periodontal diseases oral mucosal diseases dental caries gastrointestinal diseases |
| title | The Impact of <i>Lactobacillus reuteri</i> on Oral and Systemic Health: A Comprehensive Review of Recent Research |
| title_full | The Impact of <i>Lactobacillus reuteri</i> on Oral and Systemic Health: A Comprehensive Review of Recent Research |
| title_fullStr | The Impact of <i>Lactobacillus reuteri</i> on Oral and Systemic Health: A Comprehensive Review of Recent Research |
| title_full_unstemmed | The Impact of <i>Lactobacillus reuteri</i> on Oral and Systemic Health: A Comprehensive Review of Recent Research |
| title_short | The Impact of <i>Lactobacillus reuteri</i> on Oral and Systemic Health: A Comprehensive Review of Recent Research |
| title_sort | impact of i lactobacillus reuteri i on oral and systemic health a comprehensive review of recent research |
| topic | <i>Lactobacillus reuteri</i> microbiome periodontal diseases oral mucosal diseases dental caries gastrointestinal diseases |
| url | https://www.mdpi.com/2076-2607/13/1/45 |
| work_keys_str_mv | AT zihuiliu theimpactofilactobacillusreuteriionoralandsystemichealthacomprehensivereviewofrecentresearch AT qingcao theimpactofilactobacillusreuteriionoralandsystemichealthacomprehensivereviewofrecentresearch AT wenqingwang theimpactofilactobacillusreuteriionoralandsystemichealthacomprehensivereviewofrecentresearch AT bowenwang theimpactofilactobacillusreuteriionoralandsystemichealthacomprehensivereviewofrecentresearch AT yilunyang theimpactofilactobacillusreuteriionoralandsystemichealthacomprehensivereviewofrecentresearch AT coryjxian theimpactofilactobacillusreuteriionoralandsystemichealthacomprehensivereviewofrecentresearch AT tiejunli theimpactofilactobacillusreuteriionoralandsystemichealthacomprehensivereviewofrecentresearch AT yuankunzhai theimpactofilactobacillusreuteriionoralandsystemichealthacomprehensivereviewofrecentresearch AT zihuiliu impactofilactobacillusreuteriionoralandsystemichealthacomprehensivereviewofrecentresearch AT qingcao impactofilactobacillusreuteriionoralandsystemichealthacomprehensivereviewofrecentresearch AT wenqingwang impactofilactobacillusreuteriionoralandsystemichealthacomprehensivereviewofrecentresearch AT bowenwang impactofilactobacillusreuteriionoralandsystemichealthacomprehensivereviewofrecentresearch AT yilunyang impactofilactobacillusreuteriionoralandsystemichealthacomprehensivereviewofrecentresearch AT coryjxian impactofilactobacillusreuteriionoralandsystemichealthacomprehensivereviewofrecentresearch AT tiejunli impactofilactobacillusreuteriionoralandsystemichealthacomprehensivereviewofrecentresearch AT yuankunzhai impactofilactobacillusreuteriionoralandsystemichealthacomprehensivereviewofrecentresearch |