Analysis of Energy Metabolism and Lipid Spatial Distribution in Hypoxic-Ischemic Encephalopathy Revealed by MALDI-MSI

Analysis of Energy Metabolism and Lipid Spatial Distribution in Hypoxic-Ischemic Encephalopathy Revealed by MALDI-MSI

<b>Background:</b> Neonatal hypoxic-ischemic encephalopathy (HIE) is a major cause of neonatal death and neurodevelopmental disorders, and its pathological mechanisms are closely related to disturbed energy metabolism and lipid remodeling. Exploring the spatial heterogeneity of metabolom...

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Bibliographic Details
Main Authors: Xingxing Zhao, Peipei Chen, Lun Yu, Chuchu Gao, Sannan Wang, Zuming Yang, Zongtai Feng
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Biomedicines
Subjects:
neonatal hypoxic-ischemic encephalopathy
spatial metabolome
energy metabolism
purine metabolism
lipid metabolism
Online Access:https://www.mdpi.com/2227-9059/13/6/1431
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