Extranuclear estrogen receptors mediate the neuroprotective effects of estrogen in the rat hippocampus.

<h4>Background</h4>17beta-estradiol (E2) has been implicated to exert neuroprotective effects in the brain following cerebral ischemia. Classically, E2 is thought to exert its effects via genomic signaling mediated by interaction with nuclear estrogen receptors. However, the role and con...

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Bibliographic Details
Main Authors: Li-cai Yang, Quan-Guang Zhang, Cai-feng Zhou, Fang Yang, Yi-dong Zhang, Rui-min Wang, Darrell W Brann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0009851&type=printable
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