Experimental Study On The Development Of Tolerance And Withdrawal Syndrome To Pentylenetetrazole-Induced Seizures In Rats Treated With Retigabine

The aim of the study was to evaluate seizure liability in rats against the convulsant pentylenetetrazole (PTZ) during a 14-day treatment with retigabine (RTG). The seizure liability was also studied on the 1st, 2nd and 3rd day after the abrupt determination of its administration. Male Wistar rats we...

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Bibliographic Details
Main Authors: Elisaveta Apostolova, Vesela Kokova, Lyudmil Peychev
Format: Article
Language:English
Published: Medical University - Pleven 2015-06-01
Series:Journal of Biomedical & Clinical Research
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Online Access:https://jbcr.arphahub.com/article/34360/download/pdf/
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