Engineered neutrophil membrane-camouflaged nanocomplexes for targeted siRNA delivery against myocardial ischemia reperfusion injury

Abstract Small interfering RNA (siRNA) therapies hold great potential for treating myocardial ischemia-reperfusion injury (MIRI); while their practical application is limited by the low bioavailability, off-target effects, and poor therapeutic efficacy. Here, we present an innovative engineered neut...

Full description

Saved in:
Bibliographic Details
Main Authors: Yaohui Jiang, Rongyan Jiang, Zequn Xia, Meng Guo, Yanan Fu, Xiaocheng Wang, Jun Xie
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Journal of Nanobiotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12951-025-03172-w
Tags: Add Tag
No Tags, Be the first to tag this record!