KAT5 knockdown alleviates microglial inflammatory injury following acute cerebral ischemia through enhanced STAT6 activity

In ischemic stroke (IS), microglia exhibit dynamic functional shifts, contributing to tissue damage during the acute phase and promoting repair in the chronic phase. The mechanisms underlying these transitions are poorly understood. We utilized a KAT5 knockdown rat model in conjunction with a BV2 ce...

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Bibliographic Details
Main Authors: Yixin Li, Li Peng, Yang Zhou, Yan You, Jin Jiang, Yong Luo
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Brain Research Bulletin
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Online Access:http://www.sciencedirect.com/science/article/pii/S0361923025002795
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