Inflammatory conditions shape phenotypic and functional characteristics of lung-resident memory T cells in mice

Inflammatory conditions shape phenotypic and functional characteristics of lung-resident memory T cells in mice

Abstract Lung tissue-resident memory T cells (TRM) are critical for the local control of respiratory tract infections caused by influenza A viruses (IAV). Here we compare TRM populations induced by intranasal adenoviral vector vaccines encoding hemagglutinin and nucleoprotein (NP) with those induced...

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Main Authors: Anna Schmidt, Jana Fuchs, Mark Dedden, Katharina Kocher, Christine Schülein, Julian Hübner, Ana Vieira Antão, Pascal Irrgang, Friederike Oltmanns, Vera Viherlehto, Natascha Leicht, Ralf Joachim Rieker, Carol Geppert, Uwe Appelt, Sebastian Zundler, Kilian Schober, Dennis Lapuente, Matthias Tenbusch
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58931-y
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