Iodine-Mediated Neutral and Selective N-Boc Deprotection

A simple, efficient, and alternative method has been developed for the N-Boc deprotection of structurally diverse protected amines. Selective removal of N-Boc groups was achieved with excellent yields under a solvent-free condition or in a solvent using iodine as a catalyst. The methodology involvin...

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Bibliographic Details
Main Authors: G. Pavan Kumar, D. Rambabu, M. V. Basaveswara Rao, Manojit Pal
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2013/916960
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