The Most Common Complications of Celiac Disease and the Impact of a Gluten-Free Diet on Their Course

Celiac disease is a gluten-sensitive, immune-mediated enteropathy that occurs in people with a genetic predisposition and leads to inflammation in the small intestine. During its course, characteristic antibodies are produced, which together with histopathological examination of material taken fr...

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Main Authors: Wiktoria Kosucka, Aleksandra Wiśniewska, Karolina Kaszyńska, Jakub Dąbek, Dominik Balik, Anna Kwaśniewska, Joanna Lara, Jagoda Kubicka, Martyna Grabowska, Karolina Grabowska
Format: Article
Language:English
Published: Nicolaus Copernicus University in Toruń 2025-06-01
Series:Quality in Sport
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Online Access:https://apcz.umk.pl/QS/article/view/60556
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author Wiktoria Kosucka
Aleksandra Wiśniewska
Karolina Kaszyńska
Jakub Dąbek
Dominik Balik
Anna Kwaśniewska
Joanna Lara
Jagoda Kubicka
Martyna Grabowska
Karolina Grabowska
author_facet Wiktoria Kosucka
Aleksandra Wiśniewska
Karolina Kaszyńska
Jakub Dąbek
Dominik Balik
Anna Kwaśniewska
Joanna Lara
Jagoda Kubicka
Martyna Grabowska
Karolina Grabowska
author_sort Wiktoria Kosucka
collection DOAJ
description Celiac disease is a gluten-sensitive, immune-mediated enteropathy that occurs in people with a genetic predisposition and leads to inflammation in the small intestine. During its course, characteristic antibodies are produced, which together with histopathological examination of material taken from the intestine, are the main elements of the diagnostic process. Depending on the symptoms present and microscopic changes, we distinguish classical, non-classical, subclinical and potential forms. The most typical presentation, in the form of gastrointestinal symptoms includes diarrhea, abdominal pain and weight disturbances. Atypical symptom, which may involve multiple other systems, are also increasingly observed. The cornerstone of treatment is a lifelong gluten-free diet that excludes all products containing wheat, barley and rye. In most cases, it helps alleviate or resolve symptoms and regenerate the intestinal mucosa. The long diagnostic process, non-adherence to the diet and resistance to treatment pose a high risk of complications at various stages of the disease, so it is important for the patient to cooperate appropriately with the doctor and nutritionist. The purpose of this paper is to review the most common complications of celiac disease and evaluate the impact of an appropriate diet on their course. 
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spelling doaj-art-e27a13ad8a1f40e09d6b0a895a05fb8b2025-08-20T03:20:04ZengNicolaus Copernicus University in ToruńQuality in Sport2450-31182025-06-014210.12775/QS.2025.42.60556The Most Common Complications of Celiac Disease and the Impact of a Gluten-Free Diet on Their CourseWiktoria Kosucka0https://orcid.org/0009-0001-1101-7364Aleksandra Wiśniewska1https://orcid.org/0009-0008-4393-0829Karolina Kaszyńska2https://orcid.org/0009-0000-6453-1159Jakub Dąbek3https://orcid.org/0009-0006-1367-7629Dominik Balik4https://orcid.org/0009-0003-9921-3056Anna Kwaśniewska5https://orcid.org/0009-0006-1080-1276Joanna Lara6https://orcid.org/0009-0000-9411-4815Jagoda Kubicka7https://orcid.org/0009-0004-6464-4777Martyna Grabowska8https://orcid.org/0009-0002-4030-8272Karolina Grabowska9https://orcid.org/0009-0006-7877-2512University Clinical Hospital No. 2 of the Medical University of Lodz: Stefana Żeromskiego 113 Street, 90-549 Lodz, PolandNikolai Pirogov Provintial Specialist Hospital in Lodz, Wólczańska 191/195 Street, 90-001 Lodz, PolandCharles Jonscher Medical Center, Milionowa 14 Street, 93-113 Lodz, PolandCharles Jonscher Medical Center, Milionowa 14 Street, 93-113 Lodz, PolandCentral Clinical Hospital of Medical University of Lodz, ul. Pomorska 251, 92-213 Lodz, PolandCharles Jonscher Medical Center, Milionowa 14 Street, 93-113 Lodz, PolandFaculty of Medicine, Medical Univeristy of Lodz, Al. Kościuszki 4, 90-419 Lodz, PolandProvincial Specialized Hospital in Zgierz, Parzęczewska 35, 95-100 Zgierz, PolandNorbert Barlicki University Clinical Hospital No. 1, Stefan Kopciński 22 Street, 90-153 Lodz, PolandFaculty of Medicine, Medical Univeristy of Lodz, Al. Kościuszki 4, 90-419 Lodz, Poland Celiac disease is a gluten-sensitive, immune-mediated enteropathy that occurs in people with a genetic predisposition and leads to inflammation in the small intestine. During its course, characteristic antibodies are produced, which together with histopathological examination of material taken from the intestine, are the main elements of the diagnostic process. Depending on the symptoms present and microscopic changes, we distinguish classical, non-classical, subclinical and potential forms. The most typical presentation, in the form of gastrointestinal symptoms includes diarrhea, abdominal pain and weight disturbances. Atypical symptom, which may involve multiple other systems, are also increasingly observed. The cornerstone of treatment is a lifelong gluten-free diet that excludes all products containing wheat, barley and rye. In most cases, it helps alleviate or resolve symptoms and regenerate the intestinal mucosa. The long diagnostic process, non-adherence to the diet and resistance to treatment pose a high risk of complications at various stages of the disease, so it is important for the patient to cooperate appropriately with the doctor and nutritionist. The purpose of this paper is to review the most common complications of celiac disease and evaluate the impact of an appropriate diet on their course.  https://apcz.umk.pl/QS/article/view/60556celiac diseasegluten-free dietanemialymphomaosteoporosisinfertility
spellingShingle Wiktoria Kosucka
Aleksandra Wiśniewska
Karolina Kaszyńska
Jakub Dąbek
Dominik Balik
Anna Kwaśniewska
Joanna Lara
Jagoda Kubicka
Martyna Grabowska
Karolina Grabowska
The Most Common Complications of Celiac Disease and the Impact of a Gluten-Free Diet on Their Course
Quality in Sport
celiac disease
gluten-free diet
anemia
lymphoma
osteoporosis
infertility
title The Most Common Complications of Celiac Disease and the Impact of a Gluten-Free Diet on Their Course
title_full The Most Common Complications of Celiac Disease and the Impact of a Gluten-Free Diet on Their Course
title_fullStr The Most Common Complications of Celiac Disease and the Impact of a Gluten-Free Diet on Their Course
title_full_unstemmed The Most Common Complications of Celiac Disease and the Impact of a Gluten-Free Diet on Their Course
title_short The Most Common Complications of Celiac Disease and the Impact of a Gluten-Free Diet on Their Course
title_sort most common complications of celiac disease and the impact of a gluten free diet on their course
topic celiac disease
gluten-free diet
anemia
lymphoma
osteoporosis
infertility
url https://apcz.umk.pl/QS/article/view/60556
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