D-Serine Production, Degradation, and Transport in ALS: Critical Role of Methodology
In mammalian systems, D-serine is perhaps the most biologically active D-amino acid described to date. D-serine is a coagonist at the NMDA-receptor, and receptor activation is dependent on D-serine binding. Because D-serine binding dramatically increases receptor affinity for glutamate, it can produ...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
|
| Series: | Neurology Research International |
| Online Access: | http://dx.doi.org/10.1155/2012/625245 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|