To recruit or to graft? Comparing the recruitment of resident non-neuronal cells by lineage reprogramming with engraftment of stem cell-derived neurons for neuronal replacement therapies
Neurons are post-mitotic cells that are not replaced once lost, leading to the need for neuronal replacement therapies for central nervous system (CNS) repair. The generation of induced pluripotent stem cell (iPSC) derived human neurons is relatively advanced, with the capacity to generate pure and...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-05-01
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| Series: | Frontiers in Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnins.2025.1589790/full |
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