The Caenorhabditis elegans mucin-like protein OSM-8 negatively regulates osmosensitive physiology via the transmembrane protein PTR-23.

The molecular mechanisms of animal cell osmoregulation are poorly understood. Genetic studies of osmoregulation in yeast have identified mucin-like proteins as critical regulators of osmosensitive signaling and gene expression. Whether mucins play similar roles in higher organisms is not known. Here...

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Bibliographic Details
Main Authors: Anne-Katrin Rohlfing, Yana Miteva, Lorenza Moronetti, Liping He, Todd Lamitina
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1001267&type=printable
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