Early life psychosocial stress increases binge-like ethanol consumption and CSF1R inhibition prevents stress-induced alterations in microglia and brain macrophage population density
Early life stress (ELS) has lasting consequences on microglia and brain macrophage function. During ELS, microglia and brain macrophages alter their engagement with synapses leading to changes in neuronal excitability. Further, ELS can induce innate immune memory formation in microglia and brain mac...
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Main Authors: | Stephen C. Gironda, Samuel W. Centanni, Jeffrey L. Weiner |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-02-01
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Series: | Brain, Behavior, & Immunity - Health |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2666354624002114 |
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