Brugia Malayi: Depletion of Glutathione by Buthionine Sulfoximine

Glutathione is an intracellular reducing agent. It is synthesized by a two-step reaction catalyzed by ?-glutamylcysteine synthetase (?GCS) and glutathione synthetase. ?GCS, which is the rate limiting enzyme in the synthesis of glutathione, is inhibited specifically by buthionine sulfoximine (BSO). T...

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Bibliographic Details
Main Author: Ayman Hussein
Format: Article
Language:English
Published: An-Najah National University 2005-08-01
Series:مجلة جامعة النجاح للأبحاث العلوم الطبيعية
Online Access:https://journals.najah.edu/media/journals/full_texts/brugia-malayi-depletion-glutathione-buthionine-sulfoximine.pdf
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