Homozygous CDKN2A/B deletions in low- and high-grade glioma: a meta-analysis of individual patient data and predictive values of p16 immunohistochemistry testing

Homozygous CDKN2A/B deletions in low- and high-grade glioma: a meta-analysis of individual patient data and predictive values of p16 immunohistochemistry testing

Abstract CDKN2A/B deletions are prognostically relevant in low- and high-grade gliomas. Data on this is derived from heterogeneous series, an accurate estimation of survival risk from homozygous CDKN2A/B deletion is missing. Besides genetic testing, p16-immunohistochemistry (IHC) as a less cost inte...

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Bibliographic Details
Main Authors: Darius Noack, Johannes Wach, Alonso Barrantes-Freer, Nils H. Nicolay, Erdem Güresir, Clemens Seidel
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Acta Neuropathologica Communications
Subjects:
CDKN2A/B
Individual patient data
Glioma
Meta-analysis
Overall survival
p16
Online Access:https://doi.org/10.1186/s40478-024-01889-7
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https://doi.org/10.1186/s40478-024-01889-7

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