Blockade of Glutamate Release by Botulinum Neurotoxin Type A in Humans: A Dermal Microdialysis Study

BACKGROUND: The analgesic action of botulinum neurotoxin type A (BoNTA) has been linked to the blockade of peripheral release of neuropeptides and neurotransmitters in animal models; however, there is no direct evidence of this in humans.

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Main Authors: Larissa Bittencourt da Silva, Ali Karshenas, Flemming W Bach, Sten Rasmussen, Lars Arendt-Nielsen, Parisa Gazerani
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Pain Research and Management
Online Access:http://dx.doi.org/10.1155/2014/410415
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author Larissa Bittencourt da Silva
Ali Karshenas
Flemming W Bach
Sten Rasmussen
Lars Arendt-Nielsen
Parisa Gazerani
author_facet Larissa Bittencourt da Silva
Ali Karshenas
Flemming W Bach
Sten Rasmussen
Lars Arendt-Nielsen
Parisa Gazerani
author_sort Larissa Bittencourt da Silva
collection DOAJ
description BACKGROUND: The analgesic action of botulinum neurotoxin type A (BoNTA) has been linked to the blockade of peripheral release of neuropeptides and neurotransmitters in animal models; however, there is no direct evidence of this in humans.
format Article
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institution Kabale University
issn 1203-6765
language English
publishDate 2014-01-01
publisher Wiley
record_format Article
series Pain Research and Management
spelling doaj-art-e1dd4bb09384466195b2dff498585fbb2025-02-03T01:12:31ZengWileyPain Research and Management1203-67652014-01-0119312613210.1155/2014/410415Blockade of Glutamate Release by Botulinum Neurotoxin Type A in Humans: A Dermal Microdialysis StudyLarissa Bittencourt da Silva0Ali Karshenas1Flemming W Bach2Sten Rasmussen3Lars Arendt-Nielsen4Parisa Gazerani5Center for Sensory-Motor Interaction, Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Aalborg, DenmarkDepartment of Neurology, Aalborg University Hospital, Aalborg, DenmarkDepartment of Neurology, Aalborg University Hospital, Aalborg, DenmarkOrthopaedic Surgery Research Unit, Aalborg Hospital Science and Innovation Center, Aalborg University Hospital, Aalborg, DenmarkCenter for Sensory-Motor Interaction, Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Aalborg, DenmarkCenter for Sensory-Motor Interaction, Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Aalborg, DenmarkBACKGROUND: The analgesic action of botulinum neurotoxin type A (BoNTA) has been linked to the blockade of peripheral release of neuropeptides and neurotransmitters in animal models; however, there is no direct evidence of this in humans.http://dx.doi.org/10.1155/2014/410415
spellingShingle Larissa Bittencourt da Silva
Ali Karshenas
Flemming W Bach
Sten Rasmussen
Lars Arendt-Nielsen
Parisa Gazerani
Blockade of Glutamate Release by Botulinum Neurotoxin Type A in Humans: A Dermal Microdialysis Study
Pain Research and Management
title Blockade of Glutamate Release by Botulinum Neurotoxin Type A in Humans: A Dermal Microdialysis Study
title_full Blockade of Glutamate Release by Botulinum Neurotoxin Type A in Humans: A Dermal Microdialysis Study
title_fullStr Blockade of Glutamate Release by Botulinum Neurotoxin Type A in Humans: A Dermal Microdialysis Study
title_full_unstemmed Blockade of Glutamate Release by Botulinum Neurotoxin Type A in Humans: A Dermal Microdialysis Study
title_short Blockade of Glutamate Release by Botulinum Neurotoxin Type A in Humans: A Dermal Microdialysis Study
title_sort blockade of glutamate release by botulinum neurotoxin type a in humans a dermal microdialysis study
url http://dx.doi.org/10.1155/2014/410415
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