Validation of stool and blood analysis compared to Inv A and ttr based direct blood qPCR assay as diagnostic tools for typhoid fever

Validation of stool and blood analysis compared to Inv A and ttr based direct blood qPCR assay as diagnostic tools for typhoid fever

Abstract Background The development of molecular techniques, such as polymerase chain reaction (qPCR), provides a promising approach for detecting S. enterica due to its rapidity, sensitivity, specificity, and resistance to interference from antibiotics, surpassing the routinely used stool and blood...

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Bibliographic Details
Main Authors: Shymaa A. Elaskary, Hanem Mohamed Badawy, Doaa S. Elgendy, Amany Mohammed Abdelmaksoud, Rasha G. Mostafa
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Microbiology
Subjects:
Typhoid fever
Salmonella infections
Stool microbiology
Blood microbiology
Polymerase chain reaction (PCR)
Tetrathionate respiration genes & Inv A gene detection
Online Access:https://doi.org/10.1186/s12866-025-04127-9
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https://doi.org/10.1186/s12866-025-04127-9

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