Can AI reveal the next generation of high-impact bone genomics targets?

Genetic studies have revealed hundreds of loci associated with bone-related phenotypes, including bone mineral density (BMD) and fracture risk. However, translating discovered loci into effective new therapies remains challenging. We review success stories including PCSK9-related drugs in cardiovasc...

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Bibliographic Details
Main Authors: Casey S. Greene, Christopher R. Gignoux, Marc Subirana-Granés, Milton Pividori, Stephanie C. Hicks, Cheryl L. Ackert-Bicknell
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Bone Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2352187225000166
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