Peripheral nerves modulate the peri-implant osteogenesis under type 2 diabetes through exosomes derived from schwann cells via miR-15b-5p/Txnip signaling axis

Peripheral nerves modulate the peri-implant osteogenesis under type 2 diabetes through exosomes derived from schwann cells via miR-15b-5p/Txnip signaling axis

Abstract Studies have shown that the prognosis of dental implant treatment in patients with diabetes is not as good as that in the non-diabetes population. The nerve plays a crucial role in bone metabolism, but the role and the mechanism of peripheral nerves in regulating peri-implant osteogenesis u...

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Bibliographic Details
Main Authors: Yingying Wang, Fang Qu, Yaqin Wu, Kengliang Lan, Yingyi Shen, Ziang Wu, Qi Zhong, Ximeng Cao, Zhen Fan, Chun Xu
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Nanobiotechnology
Subjects:
Dental implant
Osteogenesis
Type 2 diabetes
Schwann cells
Exosome
Online Access:https://doi.org/10.1186/s12951-025-03160-0
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