Perfluorooctanoic acid induces abnormal heart development via aryl hydrocarbon receptor-mediated oxidative stress and apoptosis in zebrafish larvae

Perfluorooctanoic acid induces abnormal heart development via aryl hydrocarbon receptor-mediated oxidative stress and apoptosis in zebrafish larvae

BackgroundIn recent years, a growing number of studies have indicated that perfluorooctanoic acid (PFOA) exposure can impact heart development, though the specific mechanisms remain elusive. The aryl hydrocarbon receptor (AHR) is a critical environmental sensor capable of inducing oxidative stress a...

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Bibliographic Details
Main Authors: Xueyi CHEN, Tianchi MA, Kang WANG, Tao CHEN, Yan JIANG
Format: Article
Language:English
Published: Editorial Committee of Journal of Environmental and Occupational Medicine 2024-12-01
Series:环境与职业医学
Subjects:
perfluorooctanoic acid
aryl hydrocarbon receptor
oxidative stress
heart development
zebrafish
Online Access:http://www.jeom.org/article/cn/10.11836/JEOM24404
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http://www.jeom.org/article/cn/10.11836/JEOM24404

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