Potential of epicatechin as antioxidant and antiaging in UV-induced BJ cells by regulating COL1A1, FGF-2, GPX-1, and MMP-1 gene, protein levels, and apoptosis

Potential of epicatechin as antioxidant and antiaging in UV-induced BJ cells by regulating COL1A1, FGF-2, GPX-1, and MMP-1 gene, protein levels, and apoptosis

Background Oxidative stress caused by exposure to ultraviolet (UV) light on the skin can damage deoxyribonucleic acid (DNA) and cause keratinocytes to undergo apoptosis. Endogenous antioxidants which play a role in trapping free radicals are also unable to overcome excess reactive oxygen species (RO...

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Bibliographic Details
Main Authors: Wahyu Widowati, Teresa Liliana Wargasetia, Fanny Rahardja, Fen Tih, Philips Onggowidjaja, Rita Tjokropranoto, Fadhilah Haifa Zahiroh, Rizal Azis, Didik Priyandoko, Wahyu Surakusumah, Dhanar Septyawan Hadiprasetyo
Format: Article
Language:English
Published: PeerJ Inc. 2024-11-01
Series:PeerJ
Subjects:
Collagen
Elastin
Epicatechin
Fibroblast
Ultraviolet
Online Access:https://peerj.com/articles/18382.pdf
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