Astragalus membranaceus extract attenuates ulcerative colitis by integrating multiomics and the PI3K/AKT signaling pathway

Astragalus membranaceus extract attenuates ulcerative colitis by integrating multiomics and the PI3K/AKT signaling pathway

IntroductionUlcerative colitis (UC) is a chronic, non-specific inflammatory bowel disease (IBD) that severely impairs the quality of life of affected individuals. Astragalus membranaceus (Fisch.) Bge. [Fabaceae; Astragali radix] (AM), a widely used Chinese medicine, has active ingredients that exhib...

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Bibliographic Details
Main Authors: Jiaying Zhu, Chenhuan Shentu, Qingling Meng, Sen Fan, Yunjia Tang, Mingjiang Mao, Xiaofeng Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Pharmacology
Subjects:
ulcerative colitis
Astragalus membranaceus
microbial dysbiosis
metabolites
PI3K/Akt signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1585748/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1585748/full

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