Specific Position of the Pulmonary Hilar Node in Cancer Immunity: Immunohistochemical and Morphometrical Study Using Lung Regional Nodes Obtained from Non-Small Cell Cancer Patients Without Metastasis

Specific Position of the Pulmonary Hilar Node in Cancer Immunity: Immunohistochemical and Morphometrical Study Using Lung Regional Nodes Obtained from Non-Small Cell Cancer Patients Without Metastasis

Background: Nodal dendritic cells (DCs) and CD169-positive macrophages, possibly monocyte-derived, cross-present cancer antigens earlier in the proximal node than in the distal node. Methods: We performed immunohistochemical and morphometric analyses to show differences in the distributions of DC-SI...

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Bibliographic Details
Main Authors: Masaya Aoki, Go Kamimura, Aya Harada-Takeda, Toshiyuki Nagata, Gen Murakami, Kazuhiro Ueda
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Lymphatics
Subjects:
lung hilar node
anticancer immunity
preconditioning along lymph flow
dendritic cells
CD169-positive macrophages
morphometry
Online Access:https://www.mdpi.com/2813-3307/3/2/13
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