Comparative performance analysis of neoepitope prediction algorithms in head and neck cancer

Comparative performance analysis of neoepitope prediction algorithms in head and neck cancer

BackgroundMutations in cancer cells can result in the production of neoepitopes that can be recognized by T cells and trigger an immune response. A reliable pipeline to identify such immunogenic neoepitopes for a given tumor would be beneficial for the design of cancer immunotherapies. Current metho...

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Bibliographic Details
Main Authors: Leila Y. Chihab, Julie G. Burel, Aaron M. Miller, Luise Westernberg, Brandee Brown, Jason Greenbaum, Michael J. Korrer, Stephen P. Schoenberger, Sebastian Joyce, Young J. Kim, Zeynep Koşaloğlu-Yalçin, Bjoern Peters
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Immunology
Subjects:
cancer
neoepitope prediction
neoepitope screening
bioinformatics
immunogenicity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1494453/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1494453/full

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